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Conference: DREAM

Date: October 2011, Friday 14th

Hour Speaker Title Presentation Video
08:45 Emilià Pola
Gustavo Stolovitzky
Andrea Califano
Miquel Ángel Pujana
Introduction to DREAM6 ok ok
09:00 Edda Klipp Cellular stress response on different levels: zooming in and out in networks ok ok
09:40 Don Sharon Long-Read RNA-Seq as a Novel Tool for Identifying Splice Variants ok ok
10:00 Nikolay Ivanov DREAM6 Challenge 1: Alternative Splicing challenge ok ok
10:20 Ramya Rangan De Novo Splice Form Discovery from RNA-Seq data ok ok
10:40 Massimiliano Orsini AuARS: A Pipeline for Transcript Discovery from RNAseq Data ok N/A
11:30 Deepak Chandran Design and Implementation of the Estimation of Model Parameters Challenge ok ok
11:50 Pablo Meyer DREAM6 Challenge 2: Estimation of Model Parameters ok ok
12:10 Po-Ru Loh Targeted Stepwise Maximum-Likelihood Estimation of Gene Regulatory Network Parameters ok ok
12:30 Clements Kreutz Experimental design and parameter estimation applied to the DREAM6 challenge ok ok
14:00 Ewan Birney ENCODE N/A ok
14:40 Danny Zeevi The Promoter Activity (Gene Expression) Predicition Challenge - Motivation and Data ok ok
15:00 Pablo Meyer DREAM6 Challenge 3: Gene Expression Prediction ok ok
15:20 Geoffrey H. Siwo A FIrST DREAM Best Performer Algorithm for Promoter Activity Prediction ok ok
15:40 Chien-Yu Chen Predicting promoter activities by non-linear combination of sequence motifs ok ok
16:30 Wade Rogers Description of the Acute Myeloid Leukemia (AML) Data Set ok ok
16:50 Rachel Norel DREAM6 Challenge 4: Molecular Classification of Acute Myeloid Leukaemia Challenge ok ok
17:10 José Vilar Multidimensional entropies for diagnosing Acute Myeloid Leukemia from patient samples using flow cytometry data N/A ok
17:30 Michael Biehl Molecular Classification of Acute Myeloid Leukaemia Challenge ok ok

 

 

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Conference: RICCI

Date: October 2011, Saturday 15th

Hour Speaker Title Presentation Video
08:45 Miguel Àngel Pujana Introduction ok ok
09:00 Manel Esteller Human Cancer Epigenomes N/A N/A
09:40 Heidi Dvinge The transcriptional landscape of miRNAs in breast cancer ok ok
10:00 Raymond Cho Temporal Dissection of Tumorigenesis in Primary Cancers ok ok
10:40 Gabriel Capellá Activating KRAS, BRAF and PIK3CA mutations converge at a transcriptional level and predict treatment response to cetuximab in colorectal cancer ok ok
11:30 Franziska Michor Evolution of the cancer genome N/A ok
12:10 Bernat Gel Characterirzation and interpretation of MPNST-associated transcriptional imbalances ok ok
13:30 Núria López-Bigas Integration and data-mining of multidimensional oncogenomic data N/A ok
14:30 Alfonso Valencia Computational Challenges in Personalize Medicine ok ok
15:10 Eva Szczurek Epistasis and more: Modeling genetic interactions in cancer ok ok
15:30 Dana Peer On the road to personalized therapy, a systems approach ok ok
16:10 Álvaro Aytes FoxO3a drives a regultatory network associated with therapeutic response in metastatic prostate cancer ok ok
17:00 Gustavo Stolovitzky Quantitative modeling in Cancer Research: Two Dynamic Stories ok ok
17:40 Gwenael Leday A flexible framework for modeling the association between DNA copy number and gene expression ok ok
18:00 Julio Sáez-Rodríguez Comparative logical models of signaling networks in normal and transformed hepatocytes N/A N/A
18:40 Christopher Maxwell BRCA1: From network analysis to carcinogenesis ok ok

 

 

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Conference: RECOMB SYSTEMS BIOLOGY PROGRAM (1st day)

Date: October 2011, Sunday 16th

Hour Speaker Title Presentation Video
08:45 am Andrea Califano Introduction N/A ok
09:00 am Barry Honig Structure-based prediction of protein-protein interactions on a genome-wide scale ok ok
09:40 am Federica Eduati Dynamic modeling of miRNA-mediated Feed-Forward Loops ok ok
10:00 am Carlo Consentino Structural Bistability of the GAL Regulatory Network and Characterization of its Domains of Attraction ok ok
10:20 am Anthony Wright Proteome-wide evidence for enhanced positive Darwinian selection within intrinsically disordered regions (IDRs) in proteins ok ok
11:10 am Sylvia Plevritis Inferring Biological Progression from High Dimensional Data ok ok
11:50 pm Jaanika Kronberg High level dynamical models in non-model species ok ok
12:10 pm Francesco Vallania Modeling the relationship between Mean and Variance in Gene Expression ok ok
12:30 pm Xiling Shen A microRNA Mediated Switch Regulates Asymmetric Division of Colon Cancer Stem Cells ok ok
02:10 pm Manolis Kellis Epigenomic views of complex disease reveal 1000s of causal variants ok ok
02:50 pm Liram Vardi A Linearized constraint based approach for modeling signaling networks ok ok
03:10 pm Yang Yinyi An S-System Parameter Estimation Method for Biological Networks ok ok
03:30 pm Tanja Vavouri Does the promoter type affect the chromatin organization within the gene? N/A ok
03:50 pm Michele Caselle The role of miRNA-mediated Feed Forward Loops in the Human Regulatory Network ok ok
04:40 pm Rune Linding Modeling of cancer kinome networks N/A ok
05:20 pm Giusseppe Jurman Biological network comparison via Ipsen-Mikhailov distance ok ok
05:40 pm Federico Morán Multi-criteria Optimization Of
Regulation in Metabolic Networks
ok ok
06:00 pm Janusz Dutkowski Protein networks as logic functions in development and cancer ok ok
06:20 pm Merja Heinaniemi Gene circuit signatures in cell type transcriptomes reveal lineage control N/A N/A
06:40 pm Daniel Marbach NetworkInference.org - A community platform for gene network inference ok ok

 

 

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Conference: RECOMB SYSTEMS BIOLOGY PROGRAM (2nd day)

Date: October 2011, Monday 17th

Hour Speaker Title Presentation Video
08:45 am Andrea Califano Introducción N/A ok
09:00 am Scott Armstrong Gene Expression and Epigenetic Control Of Leukemia Stem Cell Development ok ok
09:40 am Yael Silberberg Large Scale Elucidation of Drug Response Pathways in Humans ok ok
10:00 am Francesco Falciani A Systems Biology Approach Identifies Molecular Networks Defining Skeletal Muscle Abnormalities in Chronic Obstructive Pulmonary Disease ok ok
10:20 am Miguel Rocha Optimization approaches for the in silico discovery of optimal targets for gene over/underexpression ok ok
11:10 am Luis Serrano M pneumoniae: Towards a full quantitative understanding of a free-living system ok ok
11:50 pm Mukesh Bansal Dissecting signaling transduction network in non small cells lung cancer ok ok
12:10 pm David Amar Using differentially correlated gene pairs for classification and regulatory analysis of expression profiles from multiple diseases ok ok
12:30 pm Antonina Mitrofanova Interrogating therapeutic response in a mouse model of aggressive prostate cancer ok ok
02:20 pm Xavier Solé Master Regulators of metastasis in early-stage colon cancer ok ok
02:40 pm Alexandra Dana Efficient manipulations of synonymous mutations for controllingtranslation rate
ok ok
03:00 pm Roee Amit Anti-cooperative and cooperative protein-protein interactions between TetR isoforms on synthetic enhancers N/A ok
03:20 pm Joan Planas-Iglesias To Bind or not To Bind: Predicting protein-protein interactions from favouring and disfavouring local structural features N/A ok
04:10 pm Dennis Vitkup Complex Genetics and Systems Biology of Autism ok ok
04:50 pm Milana Morgenstern Chimeras taking shape: Potential functions of proteins encoded by chimeric RNA transcripts ok ok
05:10 pm Tamir Tuller Global map of physical interactions among differentially expressed genes in multiple sclerosis relapses and remissions ok ok
05:30 pm Edwing Wang The human phosphotyrosine signaling network- evolution and hotspots of hijacking in cancer ok ok

 

 

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Conference: RECOMB REGULATORY GENOMICS PROGRAM

Date: October 2011, Tuesday 18th

Hour Speaker Title Presentation Video
08:45 am Manolis Kellis Introduction ok ok
09:00 am Gary D Stormo Predicting DNA-binding specificity from protein sequence N/A ok
09:40 am Emi Tanaka Improved similarity scores for comparing motifs ok ok
10:00 am Roee Amit Building enhancers from the ground up: a synthetic biology approach N/A ok
10:20 am Gary D Stormo Fast, sensitive discovery of conserved genome-wide motifs N/A ok
11:10 am Alexander Stark Regulatory genomics in Drosophila N/A ok
11:50 pm Armita Nourmohammad Formation and Conservation of Regulatory
Binding Site Complexes
ok ok
12:10 pm Marina Naval Cross-­‐species Tag-­‐Seq reveals a conserved Glass targetome underlying photoreceptor cell specification in Drosophila ok ok
12:30 pm Rahul Siddharthan Evolution of binding sites in yeast ok ok
12:50 pm Quaid Morris Profiling and initial analysis of 56 Drophosila RNA-binding protein binding preferences using RNAcompete N/A ok
02:30 pm Jonathan K Pritchard Variation in chromatin accessibility is a key determinant of heritable variation in gene expression N/A ok
03:10 pm Mathieu Clément-Ziza Determining the genetic contribution to transcript variation through RNA deep sequencing
ok ok
03:30 pm Marit Ackermann The impact of genetic variation on gene
expression dynamics
ok ok
03:50 pm Roger Pique-Regi Variation in transcription factor binding
inferred by DNase-seq assays provides
molecular mechanisms for gene
expression variation
ok ok
04:10 pm Daphne Ezer Mechanistic model of how AT repeats influence gene expression ok N/A
05:00 pm Mitchell Guttman Functional integration of lincRNAs in the molecular circuitry of the cell ok ok
05:20 pm Andrea Tanzer Regulation of Regulators: Small ncRNA - Host Gene Relationships ok N/A
06:00 pm Hadas Zur Determinants of Translation Initiation in Eukaryotes ok ok
06:20 pm Aly Azeem Khan Identifying non-canonical microRNA targeting with differential CLIP-seq ok ok

Conference: RECOMB REGULATORY GENOMICS PROGRAM

Date: October 2011, Wednesday 19th

Hour Speaker Title Presentation Video
08:45 am Manolis Kellis Introduction N/A N/A
09:00 am Martha L Bulyk Transcription Factors and DNA Regulatory Elements ok ok
09:40 am Carine Gubelmann DNA-centered identification and mapping of metazoan transcription factor-DNA interactions within regulatory elements ok ok
10:00 am Aleksander Jankowski Predicting cell type-specific transcription factor cooperative binding ok ok
10:20 am Stein Aerts CisTargetX 2.0 Genome-wide integration of regulatory features for the discovery of CRMs in Drosophila ok ok
11:10 am Eileen E Furlong Making global predictions of cis-regulatory activity N/A ok
11:50 pm Thu Hang Pham Dynamic epigenetic enhancer signatures are predictive for key transcriptional regulators associated with cellular di!erentiation states ok ok
12:10 pm Thomas Sakoparnig Binding pro les of chromatin-modifying proteins are predictive for transcriptional activity and promoter-proximal pausing ok ok
12:30 pm Ivan Costa Inferring gene expression from histone modifications and transcription factor affinity on lymphoid cell development ok ok
12:50 pm Christel Goudot The reconstruction of condition-specific transcriptional modules provides new insights in the evolution of yeast AP-1 proteins N/A ok
02:30 pm Andrea Califano MicroRNA-mediated regulation accounts for missing genetic variability in Glioblastoma ok ok
03:10 pm Thierry Forné Modulated contact frequencies at gene-rich loci support a statistical helix model for mmalian chromatin organization ok ok
03:30 pm Sagi Shapira N/A N/A ok
03:50 pm Francis Chin MetaCluster 4.0: A Novel Binning Algorithm for NGS Reads and Huge Number of Species ok ok
04:10 pm Alex Greenfield Incorporating Prior Knowledge Into Network Inference
ok ok

 

 

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